Slocumb's syndrome
Related people
A condition resulting from prolonged therapy of rheumatoid arthritis with corticoid steroids. It is characterized by diurnal cycles of tiredness; muscle weakness, mostly of the thighs; aching and tightness of the muscles and joints, changes in mood, emotional instability, temperature lability, mild tendon hyperreflexia, and difficulty in making voluntary movements. In severe forms there is a panmesenchymal reaction with adrenal insufficiency and erythema-like symptoms as well as panarteriitis and phlebitis.
Bibliography
- C. H. Slocumb:
Rheumatic complaints during chronic hypercortisonism and syndromes during withdrawal of cortisone in rheumatic patients.
Proceedings of the Staff Meetings of the Mayo Clinic, Rochester, 1953, 28: 655-657. - C. H. Slocumb:
Rheumatoid arthritis. In, J. Brown and G. M. Pearson, editors: Clinical Use of Adrenal Steroids, pp 30-43. New York, McGraw-Hill, 1962. - G. T. Perkoff, R. Silber, F. H. Tyler, et al:
Myopathy due to the administration of therapeutic amounts of 17- hydroxycorticosteroids.
American Journal of Medicine, 1959, 26: 981-988.